MEET OUR RESEARCHERS
CONquer CANcer Now GRANT AWARDS
CONCERN Foundation has raised over $70 million for cancer research during its 52 year history. Since 1968, Concern Foundation has funded well over 800 pediatric and adult cancer researchers worldwide studying many forms of cancer, primarily in the areas of immunology, immunotherapy, and the genetics of cancer. Concern specifically funds researchers who lack financial support for their first major research project and provides critically needed start-up funds for promising projects. By focusing funding to new investigators, Concern helps to bridge a gap that currently exists in the scientific research community. It is difficult for new investigators to obtain initial grants from major funding sources without sound data. At the same time, it is difficult to obtain sound data without funding.
CONGRATULATIONS TO THE CONCERN FOUNDATION 2020-2022
CONQUER CANCER NOW GRANT RECIPIENTS
Irfan Asangani, Ph.D. Perelman School of Medicine, University of Pennsylvania
“Towards understanding and targeting transcriptional addiction in advanced prostate cancer.”
Christian Badr, Ph.D. Massachusetts General Hospital
Targeting Fatty acid biosynthesis in Glioblastoma
Remi Buisson, Ph.D. University of California, Irvine
APOBEC3A REGULATION IN CANCER BY THE DNA DAMAGE RESPONSE
Taran Gujral, Ph.D. Fred Hutchinson Cancer Research Center
Targeting Developmental Circuits for Immune Re-programming
Stavroula Hatzios, Ph.D. Yale University
Connecting Cysteine Oxidation to Cancer Cell Signaling in Infection-associated Cancers
Kyoung Eun Lee, Ph.D. University of Michigan
Role of Hypoxia in B cell Migration and Function in Pancreatic Cancer
Chao Lu, Ph.D. Columbia University
Role of Histone Methyltransferase NSD1 in Squamous Cell Carcinoma Immune Evasion
Rui Lu, Ph.D. University of Alabama at Birmingham
A Transcriptional Vulnerability in Acute Myeloid Leukemia
Julia Maxson, Ph.D. Oregon Health & Science University
Mechanisms of kinase inhibitor resistance in Chronic Neutrophilic Leukemia
Vu Ngo, Ph.D. City of Hope, Beckman Research Institute
The role of CEACAM1 in oncogenic B-cell receptor signaling in mantle cell lymphoma
Elena Piskounova, Ph.D. Weill Cornell Medicine
Determining the role and regulation of de novo NADP+ synthesis in melanoma metastasis
Marjan Rafat, Ph.D. Vanderbilt University
Radiation-Induced Pre-Metastatic Niche Formation in Breast Cancer Recurrence
Evanthia Roussos Torres, Ph.D. University of Southern California
Optimizing immunotherapy by reprogramming the suppressive tumor microenvironment of breast cancer
Stephano Spano Mello, Ph.D. University of Rochester
Mechanisms underlying Neat1 function in preserving the identity of pancreatic cells
“Towards understanding and targeting transcriptional addiction in advanced prostate cancer.”
Christian Badr, Ph.D. Massachusetts General Hospital
Targeting Fatty acid biosynthesis in Glioblastoma
Remi Buisson, Ph.D. University of California, Irvine
APOBEC3A REGULATION IN CANCER BY THE DNA DAMAGE RESPONSE
Taran Gujral, Ph.D. Fred Hutchinson Cancer Research Center
Targeting Developmental Circuits for Immune Re-programming
Stavroula Hatzios, Ph.D. Yale University
Connecting Cysteine Oxidation to Cancer Cell Signaling in Infection-associated Cancers
Kyoung Eun Lee, Ph.D. University of Michigan
Role of Hypoxia in B cell Migration and Function in Pancreatic Cancer
Chao Lu, Ph.D. Columbia University
Role of Histone Methyltransferase NSD1 in Squamous Cell Carcinoma Immune Evasion
Rui Lu, Ph.D. University of Alabama at Birmingham
A Transcriptional Vulnerability in Acute Myeloid Leukemia
Julia Maxson, Ph.D. Oregon Health & Science University
Mechanisms of kinase inhibitor resistance in Chronic Neutrophilic Leukemia
Vu Ngo, Ph.D. City of Hope, Beckman Research Institute
The role of CEACAM1 in oncogenic B-cell receptor signaling in mantle cell lymphoma
Elena Piskounova, Ph.D. Weill Cornell Medicine
Determining the role and regulation of de novo NADP+ synthesis in melanoma metastasis
Marjan Rafat, Ph.D. Vanderbilt University
Radiation-Induced Pre-Metastatic Niche Formation in Breast Cancer Recurrence
Evanthia Roussos Torres, Ph.D. University of Southern California
Optimizing immunotherapy by reprogramming the suppressive tumor microenvironment of breast cancer
Stephano Spano Mello, Ph.D. University of Rochester
Mechanisms underlying Neat1 function in preserving the identity of pancreatic cells
CONCERN FOUNDATION 2018 - 2020
CONQUER CANCER NOW GRANT RECIPIENTS
Lukas Edward Dow Ph.D. - Joan & Sanford I. Weill Medical College of Cornell University
Colon Cancer: Targeting cancer-specific vulnerabilities in the WNT pathway
Moshe Elkabets Ph.D. - Ben-Gurion University of the Negev
Ovarian Cancer - Molecular Mechanisms: Underlying the molecular mechanisms of resistance of PI3Ka in ovarian cancer
Robert Babak Faryabi Ph.D. - University of Pennsylvania School of Medicine Breast Cancer Epigenetic mechanisms
Breast Cancer: Notch-driven Epigenetic Program of Triple-Negative Breast Cancer
Lydia Finley Ph.D. - Memorial Sloan-Kettering Cancer Center
Pancreatic Cancer & Cancer Metabolism: p53-driven a-ketoglutarate accumulation promotes tumor suppression
Malay Haldar MD., PhD. - The Trustees of the University of Pennsylvania Malignant
Sarcoma & Immune evasion by cancer: Targeting tumor-infiltrating antigen presenting cells for immunotherapy
Tae-Hee Kim Ph.D. - The Hospital for Sick Children (Toronto, Canada)
Gastric (i.e. stomach) Cancer Epigenetics: Epigenetic mechanisms of gastric tumorigenesis
Antonis Kourtidis Ph.D. - Medical University of South Carolina
Colon Cancer/miRNA: The Adherens Junctions orchestrate a tumor suppressing program via RNAi
Philip Kranzusch Ph.D.: Dana-Farber Cancer Institute
Any Cancer/Immunotherapy: Mechanism of human cGAS–DNA recognition and antitumor immune activation
Selma Masri Ph.D. - The Regents of the University of California (Irvine)
Lung Cancer and the environment effect on cancer: Circadian Sphingosine Signaling mediates Tumor/Host Crosstalk
Sara Meyer Ph.D. - Thomas Jefferson University
Leukemia (AML): Deciphering Non-Coding RNA Signaling in Acute Myeloid Leukemia
Anoop Patel M.D. - University of Washington
Brain Cancer (glioblastoma): Modeling intratumoral heterogeneity in glioblastoma using brain organoids
Yuliya Pylayeva-Gupta Ph.D. - The University of North Carolina at Chapel Hill
Pancreatic Cancer: Role of IL35 in immunotherapy resistance in pancreatic cancer
Boyang Wu Ph.D. - Washington State University
Prostate Cancer/Tumor Microenvironment: Dissecting stromal signals to target prostate cancer microenvironment
Yanzhong Yang M.D., Ph.D. - Beckman Research Institute of the City of Hope
Breast Cancer/Tumor Metabolism: Targeting Metabolic Pathways in Breast Cancer
Franklin Zhong Ph.D. - Institute of Medical Biology, Biomedical Sciences Institute, A*STAR (Singapore)
Skin Cancer & Cancer cell death mechanism: Pharmacologic inflammasome activation to treat SCCs
Colon Cancer: Targeting cancer-specific vulnerabilities in the WNT pathway
Moshe Elkabets Ph.D. - Ben-Gurion University of the Negev
Ovarian Cancer - Molecular Mechanisms: Underlying the molecular mechanisms of resistance of PI3Ka in ovarian cancer
Robert Babak Faryabi Ph.D. - University of Pennsylvania School of Medicine Breast Cancer Epigenetic mechanisms
Breast Cancer: Notch-driven Epigenetic Program of Triple-Negative Breast Cancer
Lydia Finley Ph.D. - Memorial Sloan-Kettering Cancer Center
Pancreatic Cancer & Cancer Metabolism: p53-driven a-ketoglutarate accumulation promotes tumor suppression
Malay Haldar MD., PhD. - The Trustees of the University of Pennsylvania Malignant
Sarcoma & Immune evasion by cancer: Targeting tumor-infiltrating antigen presenting cells for immunotherapy
Tae-Hee Kim Ph.D. - The Hospital for Sick Children (Toronto, Canada)
Gastric (i.e. stomach) Cancer Epigenetics: Epigenetic mechanisms of gastric tumorigenesis
Antonis Kourtidis Ph.D. - Medical University of South Carolina
Colon Cancer/miRNA: The Adherens Junctions orchestrate a tumor suppressing program via RNAi
Philip Kranzusch Ph.D.: Dana-Farber Cancer Institute
Any Cancer/Immunotherapy: Mechanism of human cGAS–DNA recognition and antitumor immune activation
Selma Masri Ph.D. - The Regents of the University of California (Irvine)
Lung Cancer and the environment effect on cancer: Circadian Sphingosine Signaling mediates Tumor/Host Crosstalk
Sara Meyer Ph.D. - Thomas Jefferson University
Leukemia (AML): Deciphering Non-Coding RNA Signaling in Acute Myeloid Leukemia
Anoop Patel M.D. - University of Washington
Brain Cancer (glioblastoma): Modeling intratumoral heterogeneity in glioblastoma using brain organoids
Yuliya Pylayeva-Gupta Ph.D. - The University of North Carolina at Chapel Hill
Pancreatic Cancer: Role of IL35 in immunotherapy resistance in pancreatic cancer
Boyang Wu Ph.D. - Washington State University
Prostate Cancer/Tumor Microenvironment: Dissecting stromal signals to target prostate cancer microenvironment
Yanzhong Yang M.D., Ph.D. - Beckman Research Institute of the City of Hope
Breast Cancer/Tumor Metabolism: Targeting Metabolic Pathways in Breast Cancer
Franklin Zhong Ph.D. - Institute of Medical Biology, Biomedical Sciences Institute, A*STAR (Singapore)
Skin Cancer & Cancer cell death mechanism: Pharmacologic inflammasome activation to treat SCCs
Concern Foundation Laboratories at Lautenberg Center for Immunology
and Cancer Research Hebrew University Jerusalem, Israel
For forty-five years, Concern Foundation has been proud to support the fine work of the men and women at the Hebrew University Hadassah Hospital’s Lautenberg Center. In 2018, following 50 years in which they were located in an old pharmacy building, they moved to a new brand facility. In their new location, the offices of all the PIs are located next to one another, enabling close interactions. They have completely new labs which are modern and fully equipped. They have a large student room where students from different labs can comfortably eat and socialize with one another and they now have a departmental equipment room which contains numerous state-of-the-art instruments. This move was made possible because of the Concern Foundation and to honor our longstanding commitment the new facility was renamed the Concern Foundation Laboratories at Lautenberg Center for Immunology and Cancer Research
An annual gift from Concern and a generous grant from the Ahmanson Foundation are the sustaining funding sources for the eleven scientists are currently heading up the research.
Rami I. Aqeilan
Michal Baniyash
Yinon Ben-Neriah
Michael Berger
Moshe Kotler
David Naor
Oren Parnas
Eli Pikarsky
Dana Wolf
Eitan Yefenof
Ofer Mandelboim – Head of the Concern Foundation Laboratories at Lautenberg Center for Immunology and Cancer Research
Here is a current progress report provided by these men and women: PROGRESS REPORT 2018
An annual gift from Concern and a generous grant from the Ahmanson Foundation are the sustaining funding sources for the eleven scientists are currently heading up the research.
Rami I. Aqeilan
Michal Baniyash
Yinon Ben-Neriah
Michael Berger
Moshe Kotler
David Naor
Oren Parnas
Eli Pikarsky
Dana Wolf
Eitan Yefenof
Ofer Mandelboim – Head of the Concern Foundation Laboratories at Lautenberg Center for Immunology and Cancer Research
Here is a current progress report provided by these men and women: PROGRESS REPORT 2018
|
The members of the Concern Foundation and the Lautenberg Center deeply mourn the passing of Prof. David Weiss, who died on July 12, 2016.
David Weiss established the Lautenberg Center for General and Tumor Immunology and served as its first Director until 1996. Over all these years, David recruited resources and personnel to the Center and structured it to be a cutting edge leading institution for research and teaching. David was a leading scientist in the arena of cancer immunology and immunotherapy with more than 200 publications in scientific journals and books. David Weiss shall be remembered as a great researcher, teacher, writer and speaker who left an unforgettable signature on the quality of science performed by Lautenberg Center scientists. |
CONCERN FOUNDATION 2016 - 2018
CONQUER CANCER NOW GRANT RECIPIENTS
Milan Chheda, (BRAIN CANCER)
Washington University in St.Louis
Chromatin remodeling in glioblastoma
Xi Huang, (BRAIN CANCER)
The Hospital for Sick Children, Toronto Canada
Targeting EAG2 potassium channel in glioblastoma
Bojana Gligorijevic, (BREAST CANCER)
Temple University
Real-‐Time Intravital Imaging of Cancer Cell Cycle and Motility States
Olga Razorenova, (BREAST CANCER)
The Regents of the University of California (Irvine)
Dissecting the role of CDCP1 in pro-‐metastatic signaling
Hyungiin Kim, (GENERAL CANCER MECHANISM)
State University of New York, Stony Brook
Mechanisms linking proteolysis to replication stress and tumorigenesis
Masataka Suzuki, (HEAD & NECK CANCER)
Baylor College of Medicine
Combining Ad gene therapy with CAR Ad-‐specific T-‐cell therapy for HNSCC
Chintan Parekh, (LEUKEMIA)
Children's Hospital, Los Angeles
Role of the long noncoding RNA DANCR in T cell acute lymphoblastic leukemia
Luis Batista, (LIVER CANCER)
Washington University in St.Louis
Telomerase modulation prevents end-‐stage liver disease and cancer
Baochun Zhang, (LYMPHOMA)
Dana-‐Farber Cancer Institute
Dual Specificity Phosphatase 2 in Diffuse Large B-Cell Lymphomagenesis
Saar Gill, (OVARIAN CANCER)
The Trustees of the University of Pennsylvania
Chimeric AntigenReceptor-‐redirected Macrophages for Solid Tumors
Kian-Huat Lim, (PANCREATIC CANCER)
Washington University in St.Louis
Neutralizing The Innate Immune Defense Mechanism Of Pancreatic Cancer
Bruno Sainz, (PANCREATIC CANCER)
Universidad Autónoma de Madrid (Autonoma University of Madrid)
Targeting mitochondrial respiration, an Achilles' heel of cancer stem cells
Scott Atwood, (SKIN CANCER)
The Regents of the University of California (Irvine)
FAT1 regulates basal cell carcinoma initiation and drug resistance
Concern Foundation Ongoing Research Grants
Karolinska Institute under the direction of George Klein, M.D.
Stockholm Sweden
**Funding matched by the Cancer Research Institute**
Concern Foundation’s annual endowment to the Karolinska Institute supported 18 researchers who are developing new and novel approaches in four areas:
A) Epstein-Barr Virus (EBV) and Kaposi Sarcoma Herpesvirus (HHV-8)
B) Oncogenes and Tumor Suppressor Genes
C) Tumor Immunology
D) Cytotoxic Drug Sensitivity
The Lautenberg Center/Hebrew University Jerusalem, Israel
For forty-four years, Concern Foundation has been proud to support the fine work of the Lautenberg Center. This annual endowment is supported by a generous grant from the Ahmanson Foundation. Fourteen scientists are currently supported by the endowment:
Rami I. Aqeilan
Michael Baniyash
Yinon Ben Neriah
Shlomo Z. Ben-Sasson
Ruth Gallily
Ygal Haupt
Shoshana Israel
Eli Kedar
Moshe Kotler
Ofer Mandelboim
David Naor
Eli Pikarsky
Michael Steinitz
Eitan Yefenof
Washington University in St.Louis
Chromatin remodeling in glioblastoma
Xi Huang, (BRAIN CANCER)
The Hospital for Sick Children, Toronto Canada
Targeting EAG2 potassium channel in glioblastoma
Bojana Gligorijevic, (BREAST CANCER)
Temple University
Real-‐Time Intravital Imaging of Cancer Cell Cycle and Motility States
Olga Razorenova, (BREAST CANCER)
The Regents of the University of California (Irvine)
Dissecting the role of CDCP1 in pro-‐metastatic signaling
Hyungiin Kim, (GENERAL CANCER MECHANISM)
State University of New York, Stony Brook
Mechanisms linking proteolysis to replication stress and tumorigenesis
Masataka Suzuki, (HEAD & NECK CANCER)
Baylor College of Medicine
Combining Ad gene therapy with CAR Ad-‐specific T-‐cell therapy for HNSCC
Chintan Parekh, (LEUKEMIA)
Children's Hospital, Los Angeles
Role of the long noncoding RNA DANCR in T cell acute lymphoblastic leukemia
Luis Batista, (LIVER CANCER)
Washington University in St.Louis
Telomerase modulation prevents end-‐stage liver disease and cancer
Baochun Zhang, (LYMPHOMA)
Dana-‐Farber Cancer Institute
Dual Specificity Phosphatase 2 in Diffuse Large B-Cell Lymphomagenesis
Saar Gill, (OVARIAN CANCER)
The Trustees of the University of Pennsylvania
Chimeric AntigenReceptor-‐redirected Macrophages for Solid Tumors
Kian-Huat Lim, (PANCREATIC CANCER)
Washington University in St.Louis
Neutralizing The Innate Immune Defense Mechanism Of Pancreatic Cancer
Bruno Sainz, (PANCREATIC CANCER)
Universidad Autónoma de Madrid (Autonoma University of Madrid)
Targeting mitochondrial respiration, an Achilles' heel of cancer stem cells
Scott Atwood, (SKIN CANCER)
The Regents of the University of California (Irvine)
FAT1 regulates basal cell carcinoma initiation and drug resistance
Concern Foundation Ongoing Research Grants
Karolinska Institute under the direction of George Klein, M.D.
Stockholm Sweden
**Funding matched by the Cancer Research Institute**
Concern Foundation’s annual endowment to the Karolinska Institute supported 18 researchers who are developing new and novel approaches in four areas:
A) Epstein-Barr Virus (EBV) and Kaposi Sarcoma Herpesvirus (HHV-8)
B) Oncogenes and Tumor Suppressor Genes
C) Tumor Immunology
D) Cytotoxic Drug Sensitivity
The Lautenberg Center/Hebrew University Jerusalem, Israel
For forty-four years, Concern Foundation has been proud to support the fine work of the Lautenberg Center. This annual endowment is supported by a generous grant from the Ahmanson Foundation. Fourteen scientists are currently supported by the endowment:
Rami I. Aqeilan
Michael Baniyash
Yinon Ben Neriah
Shlomo Z. Ben-Sasson
Ruth Gallily
Ygal Haupt
Shoshana Israel
Eli Kedar
Moshe Kotler
Ofer Mandelboim
David Naor
Eli Pikarsky
Michael Steinitz
Eitan Yefenof
INDEPENDENT GRANT AWARDS GIVEN BY CONCERN FOUNDATION
BREAST CANCER
City of Hope
Phase I/II Study Combining Chemotherapy, AKT3 Targeted Therapy, and Immune Checkpoint Inhibitors in Patients with Metastatic Triple Negative Breast Cancer - Dr. Yuan Yuan
**The grant is provided by Concern Foundation and The Marni Fund and Bruce and Lynn Kaufman,
THE ADOLESCENT AND YOUNG ADULT (AYA@USC) PROGRAM
"Germ Cell Tumors Study” with Dr. Victoria Cortessis and Dr. James Hu
PEDIATRIC CANCER – BRAIN TUMOR “Novel Molecular Model of P1D1 Function in Pediatric Brain Tumors”Anat Epstein
Children’s Hospital Los Angeles
**The grant is provided by Concern Foundation and Terri and Jerry Kohl.
BREAST CANCER
USC Norris Comprehensive Cancer Center
Dr. Adam de Smith. Ph.D.
“Second malignancies in breast cancer survivors: deciphering the genetic risk”
**This grant is provided by The Marni Fund, Kaufman & Levine Families, and Concern Foundation.
THE ADOLESCENT AND YOUNG ADULT (AYA@USC) PROGRAM Tissue Registry, Social Worker & Data Coordinator
USC Norris Comprehensive Cancer Center & Children’s Hospital Los Angeles
** This grant is co-funded by Marion Brucker Legacy Fund**
THE ADOLESCENT AND YOUNG ADULT (AYA@USC) PROGRAMLOS ANGELES UNIFIED SCHOOL DISTRICT
Pilot Testicular Cancer project for early detection/self-examinations by students
**This grant funded by a portion of the proceeds raised during the 2016 LA marathon**
POPULATION SCIENCES – SECONDARY CANCER DEVELOPMENT- “Disparities in Adolescent & Young Adult Cancers” Julie Wolfson, M.D.
City of Hope
**Funding matched by the Teller & Shapiro Family**
CONCERN FOUNDATION STEM CELL RESEARCH AWARD “Conquering Germ Cell Tumors in Children and Young Adults”
Dr. Amander Clark, PhD
UCLA Broad Stem Cell Research Center
**This grant is co-funded by Wendy & Tom Nogradi and NSBN**
UNDERSTANDING THE RELATIONSHIP BETWEEN LOW TESTOSTERONE and PROSTATE CANCER RISKDr. Jeremy Jones
City of Hope
**This grant is co-funded Myrna & Stan Zimmerman and the Marion Brucker Legacy Fund**
PROSTATE CANCER “Identification and Functional Characterization of Kinases Driving Prostate Cancer Metastasis to Bone” Dr. Owen Witte
UCLA Broad Stem Cell Research Center
**This grant is funded through Concern by Myrna & Stanley Zimmerman**
CONCERN FOUNDATION 2014 -2016
CONquer CANcer Now GRANT RECIPIENTS
Mark Chiang
The Regents of the University of Michigan
The collaboration between NOTCH1 and ZMIZ1 in T-cell leukemia
Jean-Francois Rual
The Regents of the University of Michigan
Aberrant epigenetic control of notch signals in medulloblastoma
Barbara Bedogni
Case Western Reserve University
Targeting a novel MT1-MMP/Notch1 interaction in melanoma
Gang Greg Wang
The University of North Carolina at Chapel Hill
The role of KDM5 histone lysine demethylases in leukemia and lymphoma
George-Lucian Moldovan
The Pennsylvania State University College of Medicine
Preservation of genetic stability during DNA replication
Elizabeth Yeh
Medical University of Southern Carolina
A Novel Targeted Approach for Triple-negative Breast Cancer
**Co-funded by the Save The Ta-tas Foundation**
Michael Boyce
Duke University Medical Center
Protein glycosylation in cancer cell signaling and metabolism
Paolo Provenzano
Regents of the University of Minnesota- Twin Cities
Stroma targeting therapy for pancreatic cancer
Ziv Granot
Hebrew University of Jerusalem
Dissecting the mechanisms of tumor-cell recognition by neutrophils
Deborah Kelly
Virginia Polytechnic Institute and State University
Molecular Basis for BRCA1 in Transcription-Coupled Repair Mechanisms
Damien Reynaud
Cincinnati Children’s Hospital Medical Center
Systemic Metabolic Disorders and Leukemic Clonal Dominance
Sarah-Maria Fendt
Vlaams Instituut voor Biotechnologie, Belgium
Regulation of amino acid metabolism and proliferation by S6K1 in cancer
Michael Berger
Hebrew University of Jerusalem - Hadassah School of Medicine
The role of the quiescence inducer, SLFN2, and its human paralogs in T-ALL
Eyal Arbely
Ben-Gurion University of the Negev
Live cell and structural studies of p53 acetylation induced apoptosis
Hae-Ri Song
New York University
Investigating the role of NFIA-NFkB axis in glioma pathogenesis
Muller Fabbri
Children's Hospital, Los Angeles
Tumor Associated Macrophages exosomic miRNAs in Neuroblastoma biology
Albert Kim
Washington University in St. Louis
Regulation of Brain Cancer Stem Cells by the Anaphase-Promoting Complex
The Regents of the University of Michigan
The collaboration between NOTCH1 and ZMIZ1 in T-cell leukemia
Jean-Francois Rual
The Regents of the University of Michigan
Aberrant epigenetic control of notch signals in medulloblastoma
Barbara Bedogni
Case Western Reserve University
Targeting a novel MT1-MMP/Notch1 interaction in melanoma
Gang Greg Wang
The University of North Carolina at Chapel Hill
The role of KDM5 histone lysine demethylases in leukemia and lymphoma
George-Lucian Moldovan
The Pennsylvania State University College of Medicine
Preservation of genetic stability during DNA replication
Elizabeth Yeh
Medical University of Southern Carolina
A Novel Targeted Approach for Triple-negative Breast Cancer
**Co-funded by the Save The Ta-tas Foundation**
Michael Boyce
Duke University Medical Center
Protein glycosylation in cancer cell signaling and metabolism
Paolo Provenzano
Regents of the University of Minnesota- Twin Cities
Stroma targeting therapy for pancreatic cancer
Ziv Granot
Hebrew University of Jerusalem
Dissecting the mechanisms of tumor-cell recognition by neutrophils
Deborah Kelly
Virginia Polytechnic Institute and State University
Molecular Basis for BRCA1 in Transcription-Coupled Repair Mechanisms
Damien Reynaud
Cincinnati Children’s Hospital Medical Center
Systemic Metabolic Disorders and Leukemic Clonal Dominance
Sarah-Maria Fendt
Vlaams Instituut voor Biotechnologie, Belgium
Regulation of amino acid metabolism and proliferation by S6K1 in cancer
Michael Berger
Hebrew University of Jerusalem - Hadassah School of Medicine
The role of the quiescence inducer, SLFN2, and its human paralogs in T-ALL
Eyal Arbely
Ben-Gurion University of the Negev
Live cell and structural studies of p53 acetylation induced apoptosis
Hae-Ri Song
New York University
Investigating the role of NFIA-NFkB axis in glioma pathogenesis
Muller Fabbri
Children's Hospital, Los Angeles
Tumor Associated Macrophages exosomic miRNAs in Neuroblastoma biology
Albert Kim
Washington University in St. Louis
Regulation of Brain Cancer Stem Cells by the Anaphase-Promoting Complex
CANCER RESEARCH AND FUNDING AWARDS GIVEN BY
CONCERN FOUNDATION OUTSIDE OF THE SCIENTIFIC REVIEW PROCESS
- PEDIATRIC CANCER – BRAIN TUMOR “Novel Molecular Model of P1D1 Function in Pediatric Brain Tumors”
Children’s Hospital Los Angeles
**Funding matched by Mrs. Mimi Feldman & NSBN**
- THE ADOLESCENT AND YOUNG ADULT (AYA@USC) PROGRAM
USC Norris Comprehensive Cancer Center & Children’s Hospital Los Angeles
** This grant is co-funded by Marion Brucker Legacy Fund**
- POPULATION SCIENCES – SECONDARY CANCER DEVELOPMENT- “Disparities in Adolescent & Young Adult Cancers”
City of Hope
**Funding matched by the Teller & Shapiro Family**
- CONCERN FOUNDATION STEM CELL RESEARCH AWARD “Conquering Germ Cell Tumors in Children and Young Adults”
UCLA Broad Stem Cell Research Center
**This grant is co-funded by Wendy & Tom Nogradi and NSBN**
- UNDERSTANDING THE RELATIONSHIP BETWEEN LOW TESTOSTERONE and PROSTATE CANCER RISK
City of Hope
**This grant is co-funded Myrna & Stan Zimmerman and the Marion Brucker Legacy Fund**
CONCERN FOUNDATION 2012 – 2014
CONquer CANcer Now GRANT RECIPIENTS
Lifeng Xu Ph.D. (BLOOD & BONE)
The Regents of the University of California (University of California Davis)
Characterizing the Role of TIN2 in Telomerase Activation
Scott Welford Ph.D. (KIDNEY – RENAL CELL)
Case Western Reserve University - School of Medicine
Modulation of the tumor microenvironment by the MIF Signaling Program.
Xaralabos Varelas Ph.D. (BREAST)
Trustees of Boston University, B U Medical Campus
Defining polarity cues that control tumor initiation and progression
Dean Tantin Ph.D. (BLOOD. BONE MARROW & LEUKEMIA)
University of Utah
Control of myeloid leukemia self-renewal
***This grant is co-funded by Wendy & Tom Nogradi***
Matthew Strout M.D., Ph.D. (BLOOD, LYMPH NODES & NON-HODGKIN LYMPHOMA)
Yale University
The Role of Immune Diversification in Lymphomagenesis
Andrew Snow Ph.D. (BLOOD, BONE MARROW, LEUKEMIA, LEUKOCYTES)
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
Differential signaling of oncogenic CARD11 mutants in lymphocytes
Matthew Pratt Ph.D. (BREAST, LUNG & PROSTATE)
USC/University of Southern California
Cancer Metabolism and Protein Glycosylation
***This grant is co-funded by the Save The Ta-Tas Foundation***
Niv Papo Ph.D. (BRAIN, BREAST LIVER & OVARIAN)
Ben-Gurion University of the Negev
Developing Antagonistic Protein Ligands for Cancer Imaging and Therapy
Sanaz Memarzadeh Ph.D., M.D. (UTERUS)
The Regents of the University of California, Los Angeles
Potential utility of a PARP inhibitor in targeting endometrial cancers
Sergei Koralov Ph.D. (LEUKEMIA, LYMPHATIC & SKIN –NON-MELANOMA)
New York University School of Medicine
Stat3 in T cells: At the crossroads of inflammation and cancer
Thomas Graeber Ph.D. (MELANOMA)
The Regents of the University of California, Los Angeles
Signaling changes that confer resistance to BRAF-targeted melanoma therapy
Boyi Gan Ph.D. (PANCREAS)
University of Texas M.D. Anderson Cancer Center
Study the impact of FoxO reactivation on pancreatic cancer treatment
Thomas Fazzio PhD (BLOOD & BONE MARROW)
University of Massachusetts Medical School
Function of the Mbd3/NURD chromatin remodeling complex in myeloid leukemias
Timothy Donahue M.D. (PANCREAS)
The Regents of the University of California, Los Angeles
Targeting The Immunosuppressive Activity of MDSC in Pancreatic Cancer
Erin Dickerson Ph.D. (OVARIAN)
University of Minnesota - Twin Cities
Targeted Approaches for Overcoming Drug Resistance in Ovarian Cancer
Weihang Chai Ph.D. (BASIC RESEARCH)
Washington State University
Function of CST in telomere maintenance and cancer cell growth
Jennifer Carew PhD (OVARIAN)
Univ of Texas Health Science Center at San Antonio
Targeting NAE: A New Strategy for Ovarian Cancer Therapy
The Regents of the University of California (University of California Davis)
Characterizing the Role of TIN2 in Telomerase Activation
Scott Welford Ph.D. (KIDNEY – RENAL CELL)
Case Western Reserve University - School of Medicine
Modulation of the tumor microenvironment by the MIF Signaling Program.
Xaralabos Varelas Ph.D. (BREAST)
Trustees of Boston University, B U Medical Campus
Defining polarity cues that control tumor initiation and progression
Dean Tantin Ph.D. (BLOOD. BONE MARROW & LEUKEMIA)
University of Utah
Control of myeloid leukemia self-renewal
***This grant is co-funded by Wendy & Tom Nogradi***
Matthew Strout M.D., Ph.D. (BLOOD, LYMPH NODES & NON-HODGKIN LYMPHOMA)
Yale University
The Role of Immune Diversification in Lymphomagenesis
Andrew Snow Ph.D. (BLOOD, BONE MARROW, LEUKEMIA, LEUKOCYTES)
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
Differential signaling of oncogenic CARD11 mutants in lymphocytes
Matthew Pratt Ph.D. (BREAST, LUNG & PROSTATE)
USC/University of Southern California
Cancer Metabolism and Protein Glycosylation
***This grant is co-funded by the Save The Ta-Tas Foundation***
Niv Papo Ph.D. (BRAIN, BREAST LIVER & OVARIAN)
Ben-Gurion University of the Negev
Developing Antagonistic Protein Ligands for Cancer Imaging and Therapy
Sanaz Memarzadeh Ph.D., M.D. (UTERUS)
The Regents of the University of California, Los Angeles
Potential utility of a PARP inhibitor in targeting endometrial cancers
Sergei Koralov Ph.D. (LEUKEMIA, LYMPHATIC & SKIN –NON-MELANOMA)
New York University School of Medicine
Stat3 in T cells: At the crossroads of inflammation and cancer
Thomas Graeber Ph.D. (MELANOMA)
The Regents of the University of California, Los Angeles
Signaling changes that confer resistance to BRAF-targeted melanoma therapy
Boyi Gan Ph.D. (PANCREAS)
University of Texas M.D. Anderson Cancer Center
Study the impact of FoxO reactivation on pancreatic cancer treatment
Thomas Fazzio PhD (BLOOD & BONE MARROW)
University of Massachusetts Medical School
Function of the Mbd3/NURD chromatin remodeling complex in myeloid leukemias
Timothy Donahue M.D. (PANCREAS)
The Regents of the University of California, Los Angeles
Targeting The Immunosuppressive Activity of MDSC in Pancreatic Cancer
Erin Dickerson Ph.D. (OVARIAN)
University of Minnesota - Twin Cities
Targeted Approaches for Overcoming Drug Resistance in Ovarian Cancer
Weihang Chai Ph.D. (BASIC RESEARCH)
Washington State University
Function of CST in telomere maintenance and cancer cell growth
Jennifer Carew PhD (OVARIAN)
Univ of Texas Health Science Center at San Antonio
Targeting NAE: A New Strategy for Ovarian Cancer Therapy
CANCER RESEARCH AND FUNDING AWARDS GIVEN BY
CONCERN FOUNDATION OUTSIDE OF THE SCIENTIFIC REVIEW PROCESS
- PEDIATRIC CANCER – BRAIN TUMOR
Children’s Hospital Los Angeles
**Funding matched by Mrs. Mimi Feldman**
- THE ADOLESCENT AND YOUNG ADULT (AYA@USC) PROGRAM
USC Norris Comprehensive Cancer Center & Children’s Hospital Los Angeles
** This grant is co-funded by Marion Brucker Legacy Fund**
- POPULATION SCIENCES – SECONDARY CANCER DEVELOPMENT
City of Hope
**Funding matched by the Teller & Shapiro Family**
- CONCERN FOUNDATION STEM CELL RESEARCH AWARD
UCLA Broad Stem Cell Research Center
**This grant is co-funded by Wendy & Tom Nogradi**
- UNDERSTANDING THE RELATIONSHIP BETWEEN LOW TESTOSTERONE and PROSTATE CANCER RISK
City of Hope
**This grant is co-funded by Merryl & David Alpert, Jessica & Eric Nicastro and Julie and Derek Alpert**
CONCERN FOUNDATION 2010 – 2012
CONquer CANcer Now GRANT RECIPIENTS
Shahab Asgharzadeh, M.D. (PEDIATRIC CANCER – Neuroblastoma)
Children’s Hospital Los Angeles, Los Angeles
Steven Bensinger, V.M.D, Ph.D. (BRAIN CANCER)
University of California, Los Angeles
Patricia Dahia, M.D., Ph.D. (CANCER GENETICS)
UT Health Science Center at San Antonio, TX
Andrea Dorfleutner, Ph.D. (BREAST CANCER)
Northwestern University, Chicago, IL
Candelaria Gomez-Manzano, M.D. (BRAIN CANCER)
University of Texas M.D. Anderson. Houston, TX
Eva Gonzalez-Suarez, Ph.D. (BREAST CANCER)
Bellvitge Institute for Biomedical Research. Barcelona, Spain
Co-Funded by The Save the Tatas Foundation
Geraldine Guasch, Ph.D. (CANCER GENETICS)
Children’s Hospital Medical Center, Cincinnati, OH
Zeynep Gumus, Ph.D. (CANCER VISUALIZATION TOOLS)
Joan & Sanford I. Weill Medical College of Cornell University, New York, NY
Li Jia, Ph.D. (PROSTATE CANCER)
Washington University in St. Louis, St. Louis, MO
Yong-Mi Kim, Ph.D., M.D., M.P.H. (PEDIATRIC CANCER – Leukemia)
Children’s Hospital Los Angeles, Los Angeles, CA
Ya-Huei Kuo, Ph.D. (LEUKEMIA
Beckman Research Institute of the City of Hope, Duarte, CA
Richard Maser, Ph.D. (LEUKEMIA)
The Jackson Laboratory, Bar Harbor, ME
Nami McCarty, Ph.D. (LYMPHOMA)
UT Health Science Center at Houston, Houston, TX
Mari Shinohara, Ph.D. (PROSTATE CANCER)
Duke University Medical Center, Durham, NC
Vera Tarakanova, Ph.D. (PEDIATRIC CANCER GENETICS)
Medical College of Wisconsin, Milwaukee, WI
Anat Epstein (PEDIATRIC CANCER – BRAIN)
Children’s Hospital Los Angeles, Los Angeles, California
Children’s Hospital Los Angeles, Los Angeles
Steven Bensinger, V.M.D, Ph.D. (BRAIN CANCER)
University of California, Los Angeles
Patricia Dahia, M.D., Ph.D. (CANCER GENETICS)
UT Health Science Center at San Antonio, TX
Andrea Dorfleutner, Ph.D. (BREAST CANCER)
Northwestern University, Chicago, IL
Candelaria Gomez-Manzano, M.D. (BRAIN CANCER)
University of Texas M.D. Anderson. Houston, TX
Eva Gonzalez-Suarez, Ph.D. (BREAST CANCER)
Bellvitge Institute for Biomedical Research. Barcelona, Spain
Co-Funded by The Save the Tatas Foundation
Geraldine Guasch, Ph.D. (CANCER GENETICS)
Children’s Hospital Medical Center, Cincinnati, OH
Zeynep Gumus, Ph.D. (CANCER VISUALIZATION TOOLS)
Joan & Sanford I. Weill Medical College of Cornell University, New York, NY
Li Jia, Ph.D. (PROSTATE CANCER)
Washington University in St. Louis, St. Louis, MO
Yong-Mi Kim, Ph.D., M.D., M.P.H. (PEDIATRIC CANCER – Leukemia)
Children’s Hospital Los Angeles, Los Angeles, CA
Ya-Huei Kuo, Ph.D. (LEUKEMIA
Beckman Research Institute of the City of Hope, Duarte, CA
Richard Maser, Ph.D. (LEUKEMIA)
The Jackson Laboratory, Bar Harbor, ME
Nami McCarty, Ph.D. (LYMPHOMA)
UT Health Science Center at Houston, Houston, TX
Mari Shinohara, Ph.D. (PROSTATE CANCER)
Duke University Medical Center, Durham, NC
Vera Tarakanova, Ph.D. (PEDIATRIC CANCER GENETICS)
Medical College of Wisconsin, Milwaukee, WI
Anat Epstein (PEDIATRIC CANCER – BRAIN)
Children’s Hospital Los Angeles, Los Angeles, California
CANCER RESEARCH AND FUNDING AWARDS GIVEN BY
CONCERN FOUNDATION OUTSIDE OF THE SCIENTIFIC REVIEW PROCESS
- THE ADOLESCENT AND YOUNG ADULT (AYA) PROGRAM
- POPULATION SCIENCES – SECONDARY CANCER DEVELOPMENT
City of Hope, Duarte, California
- HEMATOLOGIC SUPPORTIVE CARE FOR CHILDREN WITH CANCER:
Kathy Ruccione
Children’s Hospital Los Angeles, Los Angeles, California
- CONCERN FOUNDATION STEM CELL RESEARCH AWARD
